Published online July 1, 2008
PEDIATRICS Vol. 122 No. 1 July 2008, pp. 216-217 (doi:10.1542/peds.2008-0834)
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LETTER TO THE EDITOR

Neonatal Hyperbilirubinemia: Don't Let Glucose-6-phosphate Dehydrogenase Deficiency off the Hook

Michael Kaplan, MB, ChB
Cathy Hammerman, MD
Department of Neonatology
Shaare Zedek Medical Center
Faculty of Medicine of the Hebrew University
Jerusalem 91031, Israel

The first 20% of the full text of this article appears below.

To the Editor.—

We read with great interest the recent article by Keren et al,1 in which factors predictive of neonatal hyperbilirubinemia were sought. We found it particularly surprising that glucose-6-phosphate dehydrogenase (G6PD) deficiency did not reach significance as a risk factor and seemed to be nonpredictive of jaundice. This finding is contrary to those of previous studies in which G6PD deficiency was found to be a major factor in the pathogenesis of hyperbilirubinemia and was highly associated . . . [Full Text of this Article]