Published online June 2, 2008
PEDIATRICS Vol. 121 No. 6 June 2008, pp. 1293-1294 (doi:10.1542/peds.2008-0511)
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LETTER TO THE EDITOR

Heated, Humidified High-Flow Nasal Cannula Therapy

Daniel J. Weiner, MD
Department of Pulmonary Medicine
Children's Hospital of Pittsburgh
Pittsburgh, PA 15213

Joseph McDonough, MS
Myrza Perez, MD

Department of Pulmonary Medicine

Jacquelyn Evans, MD
William Fox, MD
Angela Hedgman, RRT
Lisa Tyler, RRT

Department of Neonatology

Howard B. Panitch, MD
Department of Pulmonary Medicine
Children's Hospital of Philadelphia
Philadelphia, PA 19104

The first 20% of the full text of this article appears below.

To the Editor.

We read with interest the recent study by Kubicka et al,1 who assessed oral cavity pressure in patients receiving highly humidified and heated gas (Vapotherm [Vapotherm, Inc, Stevensville, MD]). They found that significant pressure could be generated only with the infant's mouth closed. We had also hypothesized that high-flow gas does not generate significant airway-distending pressure.

In the Neonatal Infant Center at the Children's Hospital of Philadelphia, we chose to study infants already being . . . [Full Text of this Article]