Published online May 1, 2008
PEDIATRICS Vol. 121 No. 5 May 2008, pp. 1070-1071 (doi:10.1542/peds.2008-0356)
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LETTER TO THE EDITOR

Overprescription of Antireflux Medications for Infants With Regurgitation: In Reply

Vikram Khoshoo, MD, PhD
Dean Edell, MD, MPH
Pediatric Specialty Center,
West Jefferson Medical Center,
Marrero, LA 70072

The first 20% of the full text of this article appears below.

The letter by Savino and Castagno confirms our data1 and suggests that trends for overprescription of antireflux medications exist widely. Similar trends have also been reported for adults.2 We would like to clarify some issues by using additional data.

TREATMENT PRACTICES

Responses from 3 large pediatric gastroenterology practices from different regions suggested that an average of 76% of the infants referred to them were already taking acid-suppressing agents, which implies that generous use of these medications is widespread. Barron et al have reported a >700% increase in prescriptions for proton-pump inhibitors (PPIs) for infants between 1999 and 2004.3 Less than 10% of . . . [Full Text of this Article]