Published online November 1, 2005
PEDIATRICS Vol. 116 No. 5 November 2005, pp. 1217-1218 (doi:10.1542/peds.2005-0726)
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COMMENTARY

Apnea Is Not Prolonged by Acid Gastroesophageal Reflux in Preterm Infants

Eduardo Bancalari, MD

Division of Neonatology,
Department of Pediatrics,
University of Miami School of Medicine,
Miami, FL 33129

Abbreviations: GER, gastroesophageal reflux

The first 20% of the full text of this article appears below.

Because of the possible association between gastroesophageal reflux (GER) and apnea in preterm infants, a large number of these infants receive treatment for GER with the expectation that it will reduce the frequency or severity of the apnea episodes.1 This is based on data from a few studies, most of them with small numbers of subjects. Most recent studies have shown no clear association between apnea of prematurity and GER and no beneficial effects of anti-GER therapy on the incidence or severity of apnea.2–7

Another indication for GER therapy is based on the possible association between reflux and chronic lung disease. Although it is possible that GER may predispose one to chronic aspiration . . . [Full Text of this Article]

Address correspondence to Eduardo Bancalari, MD, Department of Pediatrics, University of Miami School of Medicine, PO Box 016960, Miami, FL 33101. E-mail: ebancalari@miami.edu




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