Published online April 1, 2005
PEDIATRICS Vol. 115 No. 4 April 2005, pp. 1115-1116 (doi:10.1542/peds.2005-0148)
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Preterm Circulatory Support Is More Complex Than Just Blood Pressure: In Reply

Michael J. Munro, MBChB, MRCP, MRCPCH
Adrian M. Walker, BSc, MSc, PhD
Charles P. Barfield, MBBS, FRACP
Ritchie Centre for Baby Health Research
Monash Institute of Reproduction and Development
Monash University and Newborn Services
Monash Medical Centre
Victoria 3168, Australia

The first 20% of the full text of this article appears below.

In Reply.—

Prompted by our study,1 Evans et al raise several issues, the central one being the usefulness of maintaining arterial blood pressure as a means of ensuring adequate cerebral blood flow (CBF).

First, they "disagree that this can be ensured solely on the basis of a mean blood pressure (MBP) of >30 mm Hg." In response, we would wholeheartedly agree, because the complexity of CBF regulation and the range of clinical conditions influencing the circulation of sick preterm infants would make such an approach clinically simplistic. Recognizing this, we have been at pains to avoid leading readers to the . . . [Full Text of this Article]


Related articles in Pediatrics:

Preterm Circulatory Support Is More Complex Than Just Blood Pressure
Nick Evans, David Osborn, and Martin Kluckow
Pediatrics 2005 115: 1114-1115. [Extract] [Full Text]