Published online November 1, 2004
PEDIATRICS Vol. 114 No. 5 November 2004, pp. 1368-1369 (doi:10.1542/peds.2004-1666)
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Hospital-Acquired Hyponatremia Is Associated With Excessive Administration of Intravenous Maintenance Fluid: In Reply

Michael L. Moritz, MD
Department of Pediatrics
Children's Hospital of Pittsburgh
Pittsburgh, PA 15213

Carlos Ayus, MD
Department of Medicine
University of Texas Health Science Center
San Antonio, TX 78229-3900

The first 20% of the full text of this article appears below.

In Reply.—

We welcome the comments of Hatherill et al, because they agree with our main contention,1 ie, that the current practice of administering hypotonic maintenance parenteral fluid therapy to children can lead to dangerous hyponatremia and is in need of change. Where we differ, however, is in how we propose to change it. Hatherill et al suggest reducing the volume of maintenance fluid rather than using isotonic saline.2 Although it is true that fluid restriction will prevent hyponatremia, we are concerned that this practice could cause harm by perpetuating a state of subclinical volume depletion. Volume depletion is common in children . . . [Full Text of this Article]


Related articles in Pediatrics:

Hospital-Acquired Hyponatremia Is Associated With Excessive Administration of Intravenous Maintenance Fluid
Mark Hatherill, Zainab Waggie, Shamiel Salie, and Andrew Argent
Pediatrics 2004 114: 1368. [Extract] [Full Text]  



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D. Bohn, E. Hoorn, and M. L Halperin
Hospital-Acquired Hyponatremia Is Associated With Excessive Administration of Intravenous Maintenance Fluid: In Reply
Pediatrics, December 1, 2004; 114(6): 1744 - 1745.
[Full Text] [PDF]