Published online November 1, 2004
PEDIATRICS Vol. 114 No. 5 November 2004, pp. 1368 (doi:10.1542/peds.2004-1350)
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Right arrow Nutrition & Metabolism

Hospital-Acquired Hyponatremia Is Associated With Excessive Administration of Intravenous Maintenance Fluid

Mark Hatherill, FCPaed
Zainab Waggie, FCPaed
Shamiel Salie, FCPaed
Andrew Argent, FCPaed

Paediatric Intensive Care Unit
Red Cross Children's Hospital and University of Cape Town
Cape Town 7700, South Africa

The first 20% of the full text of this article appears below.

To the Editor.

Hoorn et al report an observational study of hospital-acquired hyponatremia.1 A larger volume of electrolyte-free water was administered to these children, compared with a control group who did not develop hyponatremia. The authors conclude that the most important causative factor was the administration of hypotonic maintenance fluid. In an accompanying commentary, Moritz and Ayus recommend that clinicians should abandon hypotonic solutions in favor of isotonic maintenance fluid.2

Because both hyponatremic and normonatremic children . . . [Full Text of this Article]


Related articles in Pediatrics:

Hospital-Acquired Hyponatremia Is Associated With Excessive Administration of Intravenous Maintenance Fluid: In Reply
Michael L. Moritz and Carlos Ayus
Pediatrics 2004 114: 1368-1369. [Extract] [Full Text]