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PEDIATRICS Vol. 114 No. 2 August 2004, pp. 547-548

SUPPLEMENT ARTICLE

EFFECTS OF MONTELUKAST AND BECLOMETHASONE ON AIRWAY FUNCTION AND ASTHMA CONTROL

James R. Banks, MD

Arnold, MD

The first 20% of the full text of this article appears below.

Israel E, Chervinsky PS, Friedman B, et al. J Allergy Clin Immunol. 2002;110:847–854


   Purpose of the Study.
 
The primary objective of asthma therapy is the maintenance of asthma control, and the most common measures of such control in clinical studies reflect pulmonary function; forced expiratory volume in 1 second (FEV1) is often used. The authors sought to use a different parameter, ie, days of asthma control, as the primary measure, because observations regarding the need for both rescue medications and unscheduled asthma-related health care are central to perceived wellness.


   Study Population.
 
This multicenter study involved 782 individuals, ≥15 years of age, with a ≥1-year history of moderate persistent asthma (baseline FEV1: 50–85% of predicted values) but no controller therapy at . . . [Full Text of this Article]