SUPPLEMENT ARTICLE |
FACTORS ASSOCIATED WITH THE DEVELOPMENT OF PEANUT ALLERGY IN CHILDHOOD
Boston, MA
| The first 20% of the full text of this article appears below. |
Lack G, Fox D, Northstone K, Golding J. N Engl J Med. 2003;348:977985
| Purpose of the Study. |
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Because peanut allergy has increased in prevalence and is an important cause of life-threatening reactions, the authors sought to investigate possible determinants of peanut allergy.
| Study Population. |
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Data were obtained from the Avon Longitudinal Study of Parents and Children. This geographically defined cohort included 13 971 preschool-aged children. Forty-nine of those children had a history of peanut allergy. Thirty-six of those 49 underwent skin testing, and 29 demonstrated positive results. Peanut allergy was confirmed for 23 children with double-blind, placebo-controlled, food challenge.
| Methods. |
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Pregnant women were enrolled and questioned about their allergy history before
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