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PEDIATRICS Vol. 114 No. 2 August 2004, pp. 521-522

SUPPLEMENT ARTICLE

THE EFFECT OF HYDROLYZED COW’S MILK FORMULA FOR ALLERGY PREVENTION IN THE FIRST YEAR OF LIFE: THE GERMAN INFANT NUTRITIONAL INTERVENTION STUDY, A RANDOMIZED, DOUBLE-BLIND TRIAL

James R. Banks, MD

Arnold, MD

The first 20% of the full text of this article appears below.

von Berg A, Koletzko S, Grubl A, et al. J Allergy Clin Immunol. 2003;111:533–540


   Purpose of the Study.
 
Feeding extensively or partially hydrolyzed formulas to infants might reduce their risk of developing allergic disorders, but the scope of benefit remains unclear. The authors sought to assess the preventive effect of different hydrolyzed formulas versus cow’s milk in a prospective study among high-risk infants.


   Study Population.
 
The subjects were 2252 infants with hereditary risk of atopy, defined as at least 1 biological parent or sibling with an allergic disease.


   Methods.
 
Infants were randomly assigned at birth, in a blinded manner, to 1 of 4 formulas, ie, cow’s milk formula (CMF), partially hydrolyzed whey formula, extensively hydrolyzed whey formula, or extensively hydrolyzed casein formula (eHF-C). However, all . . . [Full Text of this Article]