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PEDIATRICS Vol. 112 No. 2 August 2003, pp. 491

EFFECTIVENESS OF COL-1492, A NONOXYNOL-9 VAGINAL GEL, ON HIV-1 TRANSMISSION IN FEMALE SEX WORKERS: A RANDOMISED, CONTROLLED TRIAL

Joseph A. Church, MD

Los Angeles, CA

The first 20% of the full text of this article appears below.

Van Damme L, Ramjee G, Alary M, et al. Lancet. 2002;360:962–964


   Purpose of the Study.
 
Nonoxynol-9, marketed as a spermicidal contraceptive, has in vitro anti-human immunodeficiency virus (HIV) activity. This study was designed to assess the effectiveness of COL-1492, a nonoxynol-9 vaginal gel, in the prevention of HIV infection in women with a high risk of HIV exposure.


   Methods.
 
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