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PEDIATRICS Vol. 110 No. 2 August 2002, pp. 463-464

ASTHMA: LEUKOTRIENE ANTAGONIST THERAPY

A Comparison of Short-Term Treatment with Inhaled Fluticasone Propionate and Zafirlukast for Patients with Persistent Asthma

Allen Adinoff, MD

Aurora, CO

The first 20% of the full text of this article appears below.

Purpose of the Study. To compare the short-term efficacy and safety of low-dose fluticasone propionate with that of oral zafirlukast therapy for patients previously treated with ß2-agonists alone, and to evaluate the potential therapeutic benefit of switching from zafirlukast to a low-dose inhaled corticosteroid.

Subjects and Methods. This study consisted of a 4-week randomized, double-blind treatment period followed by a 4-week open-label period. Two hundred . . . [Full Text of this Article]


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