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PEDIATRICS Vol. 110 No. 2 August 2002, pp. 442-443

ALLERGY: THE UPPER AIRWAY

Cognitive and Other Adverse Effects of Diphenhydramine Use in Hospitalized Older Patients

Allen Adinoff, MD

Aurora, CO

The first 20% of the full text of this article appears below.

Purpose of the Study. Diphenhydramine hydrochloride is a commonly prescribed medicine in hospitalized patients, but its adverse effects on older patients remain unclear.

Study Population and Methods. A total of 426 hospitalized medical patients aged 70 years or older were enrolled in a prospective cohort study in a university hospital. Measurements included baseline and daily assessments including Mini-Mental State Examination scores, Confusion Assessment Method ratings, . . . [Full Text of this Article]


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