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PEDIATRICS Vol. 110 No. 2 August 2002, pp. 438

ALLERGY: ANAPHYLAXIS

Treatment of 193 Episodes of Laryngeal Edema with C1 Inhibitor Concentrate in Patients with Hereditary Angioedema

Allen Adinoff, MD

Aurora, CO

The first 20% of the full text of this article appears below.

Purpose. Hereditary angioedema (HAE) is an autosomal dominant disease (Mendelian Inheritance in Man 106100) caused by an inherited deficiency of C1 inhibitor (C1-INH) function. The clinical symptoms include skin swelling, abdominal pain, and life-threatening episodes of upper airway obstruction. The authors evaluated the efficacy of C1-INH concentrate for treating sudden airway compromise.

Patient Population and Methods. A series of 95 patients with HAE and a functional deficiency of C1-INH belonging to 59 . . . [Full Text of this Article]


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