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PEDIATRICS Vol. 108 No. 6 December 2001, pp. 1366

COMMENTARY

Zinc Supplementation Saves the Lives of Children Living in Poverty

Abbreviations: SGA, small for gestational age • IUGR, intrauterine growth retardation

The study by Sazawal et al1 analyzes the effect of zinc supplementation, during the first 9 months of life, in preventing death in infants born small for gestational age (SGA) in slum areas of India. The study was randomized and controlled for most relevant confounding variables. The main finding is that supplemental zinc in conjunction with 1 or more of other micronutrients—riboflavin, folate, calcium, phosphorus, or iron—decreases the risk of death by two thirds during the supplementation period. The risk reduction was significant and of similar magnitude independent of whether the infant was breastfed or received artificial feeding. Unfortunately this analysis was not performed for the exclusively breastfed . . . [Full Text of this Article]

Carlos Castillo-Durán, MD and Ricardo Uauy, MD, PhD

Institute of Nutrition and Food Technology (INTA)
Universidad de Chile
Macul 5540, Santiago, Chile