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Cytomegalovirus Infection

PEDIATRICS Vol. 107 No. 5 May 2001, pp. 1227-1228

Secondary Maternal Cytomegalovirus Infection---A Significant Cause of Congenital Disease

The first 20% of the full text of this article appears below.

To the Editor.

In November 1999 a comprehensive report by us on a Swedish long-term prospective study of congenital cytomegalovirus (CMV) infection was published in the Scandinavian Journal of Infectious Diseases.1 The main observation---already reported in 19842---was that secondary (recurrent) maternal CMV infection seems to be an important cause of congenital CMV disease. Data from England (1983)3 and Belgium (1999)4 indicate a similar situation as in Sweden. While our report (1999) was in press, a US report from Alabama (1999)5 was published in the present journal with the same signification. The new US data were contrary to those reported by the same group as late as in 1992.6,7 The new unanimous findings have weighty consequences.

The Swedish study1 was based on observations made in infants born in 1977-1985. Congenital infection was identified from newborn virologic screening at the General Hospital in Malmö, Sweden. . . . [Full Text of this Article]




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Obstet GynecolHome page
S. Lipitz, R. Achiron, Y. Zalel, E. Mendelson, M. Tepperberg, and R. Gamzu
Outcome of Pregnancies With Vertical Transmission of Primary Cytomegalovirus Infection
Obstet. Gynecol., September 1, 2002; 100(3): 428 - 433.
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