PEDIATRICS Vol. 107 No. 5 May 2001, pp. 1227-1228
A Significant
Cause of Congenital Disease
| The first 20% of the full text of this article appears below. |
To the Editor.
In November 1999 a comprehensive report by us on a Swedish
long-term prospective study of congenital cytomegalovirus (CMV) infection was published in the Scandinavian Journal of Infectious Diseases.1 The main observation
already reported in
19842
was that secondary (recurrent) maternal CMV
infection seems to be an important cause of congenital CMV disease.
Data from England (1983)3 and Belgium (1999)4
indicate a similar situation as in Sweden. While our report (1999) was
in press, a US report from Alabama (1999)5 was published
in the present journal with the same signification. The new US data
were contrary to those reported by the same group as late as in
1992.6,7 The new unanimous findings have weighty
consequences.
The Swedish study1 was based on observations made in
infants born in 1977-1985. Congenital infection was identified from
newborn virologic screening at the General Hospital in Malmö,
Sweden.
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