PEDIATRICS Vol. 107 No. 2 February 2001, pp. 411-412
COMMENTARY:
Is There an Epidemic of Autism?
| The first 20% of the full text of this article appears below. |
The debate on the hypothesis of a secular increase in rates of autism would benefit from a clear recognition of the methodologic limitations of existing data. No psychiatric case register study has ever allowed for estimating and monitoring the incidence of autistic conditions over time.1 Cross-sectional surveys hugely differ in their case definition and case identification methods that account for large variations in prevalence estimates both over time and across areas, precluding a meaningful analysis of time trends. That rates in recent surveys are substantially higher than 30 years ago merely reflects the adoption of a much broader concept of autism, a recognition of autism among normally intelligent subjects, changes in diagnostic criteria, and an improved identification of persons with autism attributable to better services.1,2 The only epidemiologic study where case definition and identification could be held constant failed to detect an increase in rates of autism in successive birth cohorts from 1972 to 1985.3
Most of the claims about the `epidemic' of autism are therefore based on referral statistics from various centers. The report of the Department of Developmental Services from California has been, and still is, widely quoted as evidence for an epidemic of autism.4 The key data of this report (Table 1 and Fig 1) need a critical examination.
| Table Removed (Available Only in the Full Text) |
| Figure Removed (Available Only in the Full Text) |
First, the figures apply to numbers rather than rates and fail to
account for changes in the size and composition of the underlying population.
This article has been cited by other articles:
![]() |
A.H.A. Latif and W.R. Williams Diagnostic trends in autistic spectrum disorders in the South Wales valleys Autism, November 1, 2007; 11(6): 479 - 487. [Abstract] [PDF] |
||||
![]() |
D. L. Leslie and A. Martin Health Care Expenditures Associated With Autism Spectrum Disorders Arch Pediatr Adolesc Med, April 1, 2007; 161(4): 350 - 355. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Silverman and J. P. Brosco Understanding Autism: Parents and Pediatricians in Historical Perspective Arch Pediatr Adolesc Med, April 1, 2007; 161(4): 392 - 398. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. E. Brachlow, K. K. Ness, M. L. McPheeters, and J. G. Gurney Comparison of Indicators for a Primary Care Medical Home Between Children With Autism or Asthma and Other Special Health Care Needs: National Survey of Children's Health Arch Pediatr Adolesc Med, April 1, 2007; 161(4): 399 - 405. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. O. Atladottir, E. T. Parner, D. Schendel, S. Dalsgaard, P. H. Thomsen, and P. Thorsen Time Trends in Reported Diagnoses of Childhood Neuropsychiatric Disorders: A Danish Cohort Study Arch Pediatr Adolesc Med, February 1, 2007; 161(2): 193 - 198. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Hillier, T. Fish, P. Cloppert, and D. Q. Beversdorf Outcomes of a Social and Vocational Skills Support Group for Adolescents and Young Adults on the Autism Spectrum Focus on Autism and Other Developmental Disabilities, January 1, 2007; 22(2): 107 - 115. [Abstract] [PDF] |
||||
![]() |
E. Fombonne, R. Zakarian, A. Bennett, L. Meng, and D. McLean-Heywood Pervasive Developmental Disorders in Montreal, Quebec, Canada: Prevalence and Links With Immunizations Pediatrics, July 1, 2006; 118(1): e139 - e150. [Abstract] [Full Text] [PDF] |
||||
![]() |
J Leask, A Leask, and N Silove Evidence for autism in folklore? Arch. Dis. Child., March 1, 2005; 90(3): 271 - 271. [Full Text] [PDF] |
||||
![]() |
S. Naqvi Review of Child and Adolescent Psychiatry Focus, October 1, 2004; 2(4): 529 - 540. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. C. Meissner, P. M. Strebel, and W. A. Orenstein Measles Vaccines and the Potential for Worldwide Eradication of Measles Pediatrics, October 1, 2004; 114(4): 1065 - 1069. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. K. Parker, B. Schwartz, J. Todd, and L. K. Pickering Thimerosal-Containing Vaccines and Autistic Spectrum Disorder: A Critical Review of Published Original Data Pediatrics, September 1, 2004; 114(3): 793 - 804. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Ip, V. Wong, M. Ho, J. Lee, and W. Wong Mercury Exposure in Children With Autistic Spectrum Disorder: Case-Control Study J Child Neurol, June 1, 2004; 19(6): 431 - 434. [Abstract] [PDF] |
||||
![]() |
F. DeStefano, T. K. Bhasin, W. W. Thompson, M. Yeargin-Allsopp, and C. Boyle Age at First Measles-Mumps-Rubella Vaccination in Children With Autism and School-Matched Control Subjects: A Population-Based Study in Metropolitan Atlanta Pediatrics, February 1, 2004; 113(2): 259 - 266. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Baird, H. Cass, and V. Slonims Diagnosis of autism BMJ, August 30, 2003; 327(7413): 488 - 493. [Full Text] [PDF] |
||||
![]() |
R Lingam, A Simmons, N Andrews, E Miller, J Stowe, and B Taylor Prevalence of autism and parentally reported triggers in a north east London population Arch. Dis. Child., August 1, 2003; 88(8): 666 - 670. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. G. Gurney, M. S. Fritz, K. K. Ness, P. Sievers, C. J. Newschaffer, and E. G. Shapiro Analysis of Prevalence Trends of Autism Spectrum Disorder in Minnesota Arch Pediatr Adolesc Med, July 1, 2003; 157(7): 622 - 627. [Abstract] [Full Text] [PDF] |
||||
![]() |
C Cans, P Guillem, J Fauconnier, P Rambaud, and P S Jouk Disabilities and trends over time in a French county, 1980-91 Arch. Dis. Child., February 1, 2003; 88(2): 114 - 117. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Yeargin-Allsopp, C. Rice, T. Karapurkar, N. Doernberg, C. Boyle, and C. Murphy Prevalence of Autism in a US Metropolitan Area JAMA, January 1, 2003; 289(1): 49 - 55. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Fombonne The Prevalence of Autism JAMA, January 1, 2003; 289(1): 87 - 89. [Full Text] [PDF] |
||||
![]() |
M. F Blaxill Any changes in prevalence of autism must be determined BMJ, February 2, 2002; 324(7332): 296 - 296. [Full Text] |
||||
![]() |
L. Smeeth, A. J Hall, L. C Rodrigues, X. Huang, P. G Smith, E. Fombonne, M. Edwardes, M. Baltzan, F E. Yazbak, J. A Kaye, et al. Measles, mumps, and rubella (MMR) vaccine and autism BMJ, July 21, 2001; 323(7305): 163 - 163. [Full Text] [PDF] |
||||
![]() |
S. Chakrabarti and E. Fombonne Pervasive Developmental Disorders in Preschool Children JAMA, June 27, 2001; 285(24): 3093 - 3099. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. L. Hyman, P. M. Rodier, and P. Davidson Pervasive Developmental Disorders in Young Children JAMA, June 27, 2001; 285(24): 3141 - 3142. [Full Text] [PDF] |
||||
![]() |
N. A. Halsey, S. L. Hyman, and the Conference Writing Panel Measles-Mumps-Rubella Vaccine and Autistic Spectrum Disorder: Report From the New Challenges in Childhood Immunizations Conference Convened in Oak Brook, Illinois, June 12-13, 2000 Pediatrics, May 1, 2001; 107(5): 84e - 84. [Abstract] [Full Text] |
||||
![]() |
L. Dales, S. J. Hammer, and N. J. Smith Time Trends in Autism and in MMR Immunization Coverage in California JAMA, March 7, 2001; 285(9): 1183 - 1185. [Abstract] [Full Text] [PDF] |
||||













