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PEDIATRICS Vol. 104 No. 5 November 1999, pp. 1124-1125

COMMENTARY:
The Pitfalls of Using Managed Care Databases in Cost-Effectiveness Research

The first 20% of the full text of this article appears below.

The article by Joffe and colleagues1 that appeared in the September 1999 issue of Pediatrics discusses cost-effectiveness of respiratory syncytial virus (RSV) prophylaxis among preterm infants. This is based on a retrospective analysis of hospitalization rates from RSV lower respiratory (tract) infection (LRI) in children with a history of prematurity (<= 36 weeks' gestation) from July 1, 1991 through March 31, 1996. This analysis2 was published in the October 1999 issue of Pediatrics. The population, obtained from a large managed care database (Northern California Kaiser Permanente), is similar to that evaluated in clinical prevention trials of a hyperimmune globulin (RespiGam) and . . . [Full Text of this Article]


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S. Joffe, T. A. Lieu, and G. J. Escobar
The Critical Role of Population-Based Epidemiology in Cost-Effectiveness Research
Pediatrics, April 1, 2000; 105(4): 862 - 863.
[Full Text]