PEDIATRICS Vol. 102 No. 2 Supplement August 1998, pp. 517
From the Department of Endocrinology and Metabolism, Children's National Medical Center, and Department of Pediatrics, George Washington University, Washington, DC.
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There is unease among pediatric
endocrinologists about the ability to correctly categorize short,
poorly growing children. Are they growth hormone (GH)-deficient,
partially deficient, or normal but short? To a great extent, this
unease is illustrated by Dr Jennifer Bell's discussion of the
inability of GH provocative test results to predict the response to GH
treatment. Short children respond to GH treatment regardless of their
results on GH provocative testing. Furthermore, it is recognized that
GH provocative testing, the standard for diagnosing GH deficiency, is
inexact. The results of GH provocative testing can vary
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