PEDIATRICS Vol. 97 No. 4 April 1996, pp. 603
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Letter To The Editor

Ricki F. Goldstein MD1

1 Duke University Medical Center, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, DUMC-3179, Durham, NC 27710

The purpose of this study1 was not to identify any single variable that, by itself, could predict neurologic or developmental outcome in premature infants. Rather, it was to further investigate the previously published finding that acidosis was one of the factors in the newborn period that was influential in predicting poor motor performance and neurologic outcome at 2 years in very low birth weight infants.2 As stated in the introduction, we sought to determine whether it was the metabolic or respiratory component of acidosis that was associated with poor outcome.