PEDIATRICS Vol. 97 No. 4 April 1996, pp. 583-584
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Preliminary Experience With Intestinal Transplantation in Infants and Children

Howard C. Filston MD1 and Paul M. Colombani MD2

1 University of Tennessee Medical Center, Departments of Surgery and Pediatrics, Knoxville, TN 37920-6999
2 Transplant Committee, American Pediatric Surgical Association, Johns Hopkins Hospital, CMSC 7-113 Baltimore, MD 21205-1901

The report from the University of Nebraska Medical Center Departments of Surgery and Pediatrics by Langnas et al1 documenting their success with intesfinal transplantation in infants and children confirms comparable data from the University of Pittsburgh Transplantation Service that intestinal transplantation is a clinically viable alternative to long-term total parenteral nutrition (TPN) in infants and children with inadequate intestinal function. Most patients considered for intestinal transplantation today are those with end-stage liver disease and short bowel syndrome. They are usually quite debilitated, are in the early stages of multiple organ failure, and have spent much of their recent lives under acute care management in the hospital.

Submitted on October 20, 1995
Accepted on October 20, 1995




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