PEDIATRICS Vol. 96 No. 3 September 1995, pp. 600-603
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The Reverse Cumulative Distribution Plot: A Graphic Method for Exploratory Analysis of Antibody Data

George F. Reed PhD1, Bruce D. Meade PhD2, and Mark C. Steinhoff MD3

1 Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda MD
2 Division of Bacterial Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville MD
3 Departments of International Health and Pediatrics, Johns Hopkins University, Baltimore, MD

Serologic data often have a wide range and commonly do not approximate a normal distribution. Means, medians, SDs, or other conventional numerical summaries of antibody data may not adequately or fully describe these complex data. The reverse cumulative distribution plot is a graphic tool that completely displays all the data, allows a rapid visual assessment of important details of the distribution, and simplifies comparison of distributions.




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