PEDIATRICS Vol. 96 No. 2 August 1995, pp. 408-409
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CROSSOVER OF PLACEBO PATIENTS TO INTRAVENOUS IMMUNOGLOBULIN CONFIRMS EFFICACY FOR PROPHYLAXIS OF BACTERIAL INFECTIONS AND REDUCTION OF HOSPITALIZATIONS IN HUMAN IMMUNODEFICIENCY VIRUS-INFECTED CHILDREN

Alan Alvarado MD1, David Fuentes MD1, and William T. Shearer MD, PhD1

1 Houston, TX

Monthly IVIG infusions reduced bacterial infections and hospitalizations in HIV-infected children. In this cohort, the benefit obtained from IVIG appeared to be independent of trimethopnim-sulfamethoxazole prophylaxis for PCP, and the benefit persisted for at least 3 years.