PEDIATRICS Vol. 95 No. 2 February 1995, pp. 203-206
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Koenig, W. J.
Right arrow Articles by Berseth, C. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Koenig, W. J.
Right arrow Articles by Berseth, C. L.

Manometrics for Preterm and Term Infants: A New Tool for Old Questions

W. J. Koenig DO1, R. P. Amarnath MD1, Victoria Hench MS2, and C. L. Berseth MD3

1 Department of Pediatrics, Mayo Clinic and Mayo Foundation, Rochester, MN
2 Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, MN
3 Department of Pediatrics, Gastroenterology Unit, Mayo Clinic and Mayo Foundation, Rochester, MN

Objective. The purpose of this study was to use low-compliance, continuous-perfusion manometry to assess motor activity responses of preterm and term infants to three different methods of feeding commonly used in neonatal intensive care units.

Methods. All 48 infants who participated in this study were assigned to one of three feeding trials using a 20-calorie/oz formula. Trial 1 varied the mode of feeding, trial 2 varied the volume of feeding, and trial 3 varied the concentration of feeding.

Results. In trial 1, small intestinal motor activity changed similarly and significantly in response to intragastric (P < .005) and transpyloric feeding (P < .02). In trial 2, feedings containing a small volume (4 mL/kg) and a larger volume (10 mL/kg) elicited significant changes in motor activity compared to that seen during fasting (P < .005). In trial 3, motor activity differed in response to varying caloric density. Motor activity failed to change in response to feedings that contained one-third-concentration formula, but it did change in response to the feedings that contained two-thirds- and full-concentration formula (P < .02). Furthermore, the onset of the motor response to feeding was inversely related to the concentration of formula (P < .01), and the duration of the fed response also was related to the concentration of formula (P < .01).

Conclusions. Gastric and transpyloric feedings are equally potent in eliciting an intestinal motor response to feeding. Furthermore, a volume as small as 4 mL/kg is sufficient to elicit such a response. However, preterm intestinal motility responses are affected significantly by changes in the caloric density of formula, suggesting that diluted formula may not provide an optimal stimulant for the preterm intestinal functional responses to feeding.

Submitted on February 22, 1994
Accepted on May 27, 1994




This article has been cited by other articles:


Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
N Bekkali, S L Hamers, M R Schipperus, J B Reitsma, P G Valerio, L Van Toledo, and M A Benninga
Duration of meconium passage in preterm and term infants
Arch. Dis. Child. Fetal Neonatal Ed., September 1, 2008; 93(5): F376 - F379.
[Abstract] [Full Text] [PDF]