PEDIATRICS Vol. 94 No. 2 August 1994, pp. 270
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PHARMACOKINETICS OF PREDNISOLONE TRANSFER TO BREAST MILK

Alan Kamada PharmD1

1 Denver, CO

Because of the low amounts of pred- nisolone recovered from breast milk, it is concluded that administration of prednisolone to nursing mothers does not appear to poise a clinically significant risk to breast-fed infants. It is also suggested that infant exposure to prednisolone through breast milk can be minimized by dosing prednisolone at infrequent intervals and avoiding nursing for at least 4 hours following a dose.