PEDIATRICS Vol. 93 No. 5 May 1994, pp. 726-729
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beca, J.
Right arrow Articles by Butt, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beca, J.
Right arrow Articles by Butt, W.

Extracorporeal Membrane Oxygenation for Refractory Septic Shock in Children

John Beca MBChB, FRACP1 and Warwick Butt MBBS, FRACP1

1 Intensive Care Unit, Royal Children's Hospital, Melbourne, Australia

Objective. To review demographic data and outcome of children who received extracorporeal membrane oxygenation (ECMO) for refractory septic shock.

Method. Review of medical charts of nine children receiving ECMO for culture-proven refractory septic shock treated in a multidisciplinary pediatric intensive care unit.

Results. Median age was 12 years and median weight was 45 kg. Median inotrope requirements (µg/kg per minute) before ECMO were dopamine, 15; dobutamine, 12.5; epinephrine, 4; and norepinephrine, 3.5. Four children received two inotropes concurrently, and five received three or more. All nine patients had severe respiratory failure; eight had evidence of other organ system dysfunction, with six having five or more organ system dysfunctions. Median PRISM score was 27. Median duration of ECMO was 137 hours. Within 24 hours of starting ECMO, 7 of 9 children had all inotropes stopped. Four patients died and five survived, all of whom are leading normal lives.

Conclusion. In this small group of children with probably fatal septic shock, ECMO was successfully supported the circulation and 5 of the 9 children survived. We suggest that septic shock should not be considered a contra-indication to ECMO.

Submitted on May 17, 1993
Accepted on October 22, 1993




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
D. M. Meyer and M. E. Jessen
Results of Extracorporeal Membrane Oxygenation in Children With Sepsis
Ann. Thorac. Surg., March 1, 1997; 63(3): 756 - 761.
[Abstract] [Full Text]

Home page
 PerfusionHome page
D. L Stewart, T. V D. Cruz, C. Ziegler, and L. J Goldsmith
The use of extracorporeal membrane oxygenation in patients with Gram-negative or viral sepsis
Perfusion, January 1, 1997; 12(1): 3 - 8.
[Abstract] [PDF]