PEDIATRICS Vol. 93 No. 2 February 1994, pp. 221-227
This Article
Right arrow Full Text (PDF)
Right arrow An erratum has been published
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Olds, D. L.
Right arrow Articles by Tatelbaum, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Olds, D. L.
Right arrow Articles by Tatelbaum, R.

Intellectual Impairment in Children of Women Who Smoke Cigarettes During Pregnancy

David L. Olds PhD1, Charles R. Henderson Jr. 2, and Robert Tatelbaum MD3

1 Department of Pediatrics, University of Rochester School of Medicine and Dentistry
2 Department of Human Development and Family Studies, Cornell University
3 University of Rochester

Objective. To examine the relationship between maternal cigarette smoking during pregnancy and children's intellectual functioning during the first 4 years of life.

Design. Prospective follow-up of participants in a randomized trial of pregnancy and infancy nurse home visitation.

Setting. Semirural community in Upstate New York.

Participants. 400 families in which the mothers registered before the 30th week of pregnancy and had no previous live births. Eighty-five percent of the mothers were either teenagers (<19 years at registration), unmarried, or poor. Analysis limited to whites who comprised 89% of the sample.

Main results. Children in the comparison group whose mothers smoked 10 or more cigarettes per day during pregnancy had Stanford-Binet scores at 3 and 4 years of age that were 4.35 (95% CI: 0.02, 8.68) points lower (after controlling for a wide range of variables) than their counterparts whose mothers did not smoke during pregnancy.

Conclusions. The results of this study add to the increasingly consistent evidence that maternal cigarette smoking during pregnancy poses a unique risk for neurodevelopmental impairment among children and provide an additional reason for pregnant women not to smoke cigarettes.

Submitted on December 3, 1992
Accepted on June 18, 1993




This article has been cited by other articles:


Home page
 Am J EpidemiolHome page
S. E. Gilman, H. Gardener, and S. L. Buka
Maternal Smoking during Pregnancy and Children's Cognitive and Physical Development: A Causal Risk Factor?
Am. J. Epidemiol., September 1, 2008; 168(5): 522 - 531.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. Yang, J. Lynch, E. S. Susser, and D. A. Lawlor
Birth Weight and Cognitive Ability in Childhood Among Siblings and Nonsiblings
Pediatrics, August 1, 2008; 122(2): e350 - e358.
[Abstract] [Full Text] [PDF]

Home page
 Psychosom. Med.Home page
S. F. Suglia, R. O. Wright, J. Schwartz, and R. J. Wright
Association Between Lung Function and Cognition Among Children in a Prospective Birth Cohort Study
Psychosom Med, April 1, 2008; 70(3): 356 - 362.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Public HealthHome page
S. E. Gilman, J. Breslau, S.V. Subramanian, B. Hitsman, and K. C. Koenen
Social Factors, Psychopathology, and Maternal Smoking During Pregnancy
Am J Public Health, March 1, 2008; 98(3): 448 - 453.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
S. F. Suglia, A. Gryparis, R. O. Wright, J. Schwartz, and R. J. Wright
Association of Black Carbon with Cognition among Children in a Prospective Birth Cohort Study
Am. J. Epidemiol., February 1, 2008; 167(3): 280 - 286.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
G. D. Batty, G. Der, and I. J. Deary
Effect of Maternal Smoking During Pregnancy on Offspring's Cognitive Ability: Empirical Evidence for Complete Confounding in the US National Longitudinal Survey of Youth
Pediatrics, September 1, 2006; 118(3): 943 - 950.
[Abstract] [Full Text] [PDF]

Home page
 J Pediatr PsycholHome page
R. P. Martin, S. C. Dombrowski, C. Mullis, J. Wisenbaker, and M. O. Huttunen
Smoking During Pregnancy: Association with Childhood Temperament, Behavior, and Academic Performance
J. Pediatr. Psychol., June 1, 2006; 31(5): 490 - 500.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
D. A. Lawlor, H. Clark, G. D. Smith, and D. A. Leon
Intrauterine Growth and Intelligence Within Sibling Pairs: Findings From the Aberdeen Children of the 1950s Cohort
Pediatrics, May 1, 2006; 117(5): e894 - e902.
[Abstract] [Full Text] [PDF]

Home page
 J Pediatr PsycholHome page
P. S. Zeskind and J. L. Gingras
Maternal Cigarette-Smoking During Pregnancy Disrupts Rhythms in Fetal Heart Rate
J. Pediatr. Psychol., January 1, 2006; 31(1): 5 - 14.
[Abstract] [Full Text] [PDF]

Home page
 Int J EpidemiolHome page
N. Breslau, N. Paneth, V. C Lucia, and R. Paneth-Pollak
Maternal smoking during pregnancy and offspring IQ
Int. J. Epidemiol., October 1, 2005; 34(5): 1047 - 1053.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
C. L. Gaworski, E. L. Carmines, A. S. Faqi, and N. Rajendran
In Utero and Lactation Exposure of Rats to 1R4F Reference Cigarette Mainstream Smoke: Effect on Prenatal and Postnatal Development
Toxicol. Sci., May 1, 2004; 79(1): 157 - 169.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. R. DiFranza, C. A. Aligne, and M. Weitzman
Prenatal and Postnatal Environmental Tobacco Smoke Exposure and Children's Health
Pediatrics, April 1, 2004; 113(4/S1): 1007 - 1015.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. R. Svoboda, S. Vijayaraghavan, and R. L. Tanguay
Nicotinic Receptors Mediate Changes in Spinal Motoneuron Development and Axonal Pathfinding in Embryonic Zebrafish Exposed to Nicotine
J. Neurosci., December 15, 2002; 22(24): 10731 - 10741.
[Abstract] [Full Text] [PDF]

Home page
 Obstet GynecolHome page
C. Oncken, H. Kranzler, P. O'Malley, P. Gendreau, and W. A. Campbell
The Effect of Cigarette Smoking on Fetal Heart Rate Characteristics
Obstet. Gynecol., May 1, 2002; 99(5): 751 - 755.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. N. Abrous, W. Adriani, M.-F. Montaron, C. Aurousseau, G. Rougon, M. Le Moal, and P. V. Piazza
Nicotine Self-Administration Impairs Hippocampal Plasticity
J. Neurosci., May 1, 2002; 22(9): 3656 - 3662.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
N. Auestad, R. Halter, R. T. Hall, M. Blatter, M. L. Bogle, W. Burks, J. R. Erickson, K. M. Fitzgerald, V. Dobson, S. M. Innis, et al.
Growth and Development in Term Infants Fed Long-Chain Polyunsaturated Fatty Acids: A Double-Masked, Randomized, Parallel, Prospective, Multivariate Study
Pediatrics, August 1, 2001; 108(2): 372 - 381.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. Dollberg, O. Fainaru, F. B. Mimouni, M. Shenhav, J. B. Lessing, and M. Kupferminc
Effect of Passive Smoking in Pregnancy on Neonatal Nucleated Red Blood Cells
Pediatrics, September 1, 2000; 106(3): 34e - 34.
[Abstract] [Full Text]

Home page
 Arch Pediatr Adolesc MedHome page
A. B. Becker, J. Manfreda, A. C. Ferguson, H. Dimich-Ward, W. T. A. Watson, and M. Chan-Yeung
Breast-feeding and Environmental Tobacco Smoke Exposure
Arch Pediatr Adolesc Med, July 1, 1999; 153(7): 689 - 691.
[Abstract] [Full Text] [PDF]

Home page
 Obstet GynecolHome page
M. YERUCHIMOVICH, S. DOLLBERG, D. W. GREEN, and F. B. MIMOUNI
Nucleated Red Blood Cells in Infants of Smoking Mothers
Obstet. Gynecol., March 1, 1999; 93(3): 403 - 406.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
D. Olds, C. R. Henderson Jr, R. Cole, J. Eckenrode, H. Kitzman, D. Luckey, L. Pettitt, K. Sidora, P. Morris, and J. Powers
Long-term Effects of Nurse Home Visitation on Children's Criminal and Antisocial Behavior: 15-Year Follow-up of a Randomized Controlled Trial
JAMA, October 14, 1998; 280(14): 1238 - 1244.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
F. Berger, F. H. Gage, and S. Vijayaraghavan
Nicotinic Receptor-Induced Apoptotic Cell Death of Hippocampal Progenitor Cells
J. Neurosci., September 1, 1998; 18(17): 6871 - 6881.
[Abstract] [Full Text] [PDF]

Home page
 J Hum LactHome page
D. Wiessinger
Watch Your Language!
J Hum Lact, March 1, 1996; 12(1): 1 - 4.
[PDF]

Home page
 JWatch GeneralHome page
SMOKING, PREGNANCY, AND CHILD IQ
Journal Watch (General), March 8, 1994; 1994(308): 4 - 4.
[Full Text]