PEDIATRICS Vol. 92 No. 6 December 1993, pp. 862-864
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Hypervitaminosis D After Prolonged Feeding With a Premature Formula

YASUSHI NAKO MD1, NAOBUMI FUKUSHIMA MD1, TAKESHI TOMOMASA MD1, KANJI NAGASHIMA MD1, and TAKAYOSHI KUROUME MD1

1 Dept of Pediatrics, Gunma University School of Medicine, Meabashi, Gunma, Japan

Hypervitaminosis D is one of the causes of severe hypercalcemia in children. Most cases of hypervitaminosis D during childhood are due to an excessive supplementation of vitamin D by physicians or parents.1,2

To prevent metabolic bone disease of prematurity (rickets of prematurity), formulas designed for premature infants ("premature formulas"), which contain more calcium and vitamin D than standard formulas, are given to premature infants in addition to human milk.1 In some cases, separate vitamin D products are also given to these infants, although requirements for vitamin D and calcium intake in the premature infant and the formerly premature infant have not been fully estimated.1

Submitted on February 16, 1993
Accepted on May 14, 1993