1 Massachusetts General Hospital, Dept of Neurology, Kennedy Building, 7th Floor, Fruit Street, Boston, MA 02114
To the Editor.
First of all I would like to congratulate Dr Scher and collaborators for their excellent paper published in Pediatrics (1993;91:128-134).1 This study is unique because of its sizable population of preterm neonates, but it fails to disclose a few points of very high interest: (1) What was the frequency of the various subtypes of subtle seizures separately? (2) Were there other clinical clues for the diagnosis of seizures in the patients with autonomic signs (like subtle seizures or signs of neurologic dysfunction)? (3) Did the patients have autonomic manifestations or subtle seizures without electrographic signature? If the answer is yes, how often? Was there a statistical assocition between these events and the electrographic seizures? Those questions are very important and may be changing the way Neonatal Neurology is practiced.