A Eutectic Mixture of Lidocaine and Prilocaine for Alleviating Vaccination Pain in Infants
1 Dept of Pediatrics, University of Oulu, Oulu, Finland
The discomfort and pain caused by vaccination may prevent some parents from having their young children vaccinated. Immunization uptake is good among school-age children, but uptake rates average only about 70% in younger children and figures as low as 25% have been reported at 19 months.1-4 Yet it would be important to achieve as high an immunization uptake as possible, since if the vaccination coverage is good enough, even nonvaccinated individuals will be protected by the herd immunity that hinders the occurrence of epidemics.1,5
Painful procedures are frightening, especially in infancy, when children do not understand what is happening to them.
Submitted on November 23, 1992Accepted on April 28, 1993
This article has been cited by other articles:
 |
|
 |
|
  J.-M. Boivin, L. Poupon-Lemarquis, W. Iraqi, R. Fay, C. Schmitt, and P. Rossignol A multifactorial strategy of pain management is associated with less pain in scheduled vaccination of children. A study realized by family practitioners in 239 children aged 4-12 years old Fam. Pract., December 1, 2008; 25(6): 423 - 429. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Carbajal, V. Biran, R. Lenclen, R. Epaud, P. Cimerman, P. Thibault, D. Annequin, F. Gold, and B. Fauroux EMLA Cream and Nitrous Oxide to Alleviate Pain Induced by Palivizumab (Synagis) Intramuscular Injections in Infants and Young Children Pediatrics, June 1, 2008; 121(6): e1591 - e1598. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Taddio, J. Manley, L. Potash, M. Ipp, M. Sgro, and V. Shah Routine Immunization Practices: Use of Topical Anesthetics and Oral Analgesics Pediatrics, September 1, 2007; 120(3): e637 - e643. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. L. Schechter, W. T. Zempsky, L. L. Cohen, P. J. McGrath, C. M. McMurtry, and N. S. Bright Pain Reduction During Pediatric Immunizations: Evidence-Based Review and Recommendations Pediatrics, May 1, 2007; 119(5): e1184 - e1198. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. O'Brien, A. Taddio, M. Ipp, M. Goldbach, and G. Koren Topical 4% Amethocaine Gel Reduces the Pain of Subcutaneous Measles-Mumps-Rubella Vaccination Pediatrics, December 1, 2004; 114(6): e720 - e724. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. T. Zempsky, J. P. Cravero, and Committee on Pediatric Emergency Medicine, and Sec Relief of Pain and Anxiety in Pediatric Patients in Emergency Medical Systems Pediatrics, November 1, 2004; 114(5): 1348 - 1356. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. J. S. Anand and and the International Evidence-Based Group for Neo Consensus Statement for the Prevention and Management of Pain in the Newborn Arch Pediatr Adolesc Med, February 1, 2001; 155(2): 173 - 180. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A B Acharya, P C Bustani, J D Phillips, N A Taub, and R M Beattie Randomised controlled trial of eutectic mixture of local anaesthetics cream for venepuncture in healthy preterm infants Arch. Dis. Child. Fetal Neonatal Ed., March 1, 1998; 78(2): 138F - 142. [Abstract] [Full Text]
|
|
|
|
|
|
E. Cohen Reis and R. Holubkov Vapocoolant Spray Is Equally Effective as EMLA Cream in Reducing Immunization Pain in School-aged Children Pediatrics, December 1, 1997; 100(6): e5 - e5. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Taddio, B. Stevens, K. Craig, P. Rastogi, S. Ben-David, A. Shennan, P. Mulligan, and G. Koren Efficacy and Safety of Lidocaine-Prilocaine Cream for Pain during Circumcision N. Engl. J. Med., April 24, 1997; 336(17): 1197 - 1201. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 REDUCING VACCINATION PAIN WITH EMLA Journal Watch (General), December 7, 1993; 1993(1207): 4 - 4. [Full Text]
|
|
