PEDIATRICS Vol. 92 No. 1 July 1993, pp. 157-160
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Bronchiolitis Obliterans: A Complication of Group B Streptococcal Disease Treated With Extracorporeal Membrane Oxygenation

DENNIS E. MAYOCK MD1, P. PEARL O'ROURKE MD2, and RAJ P. KAPUR MD, PHD3

1 Division of Neonatal and Respiratory Diseases, Dept of Pediatrics, Children's Hospital and Medical Center and University of Washington School of Medicine, Seattle
2 Division of Pediatric Anesthesia, Dept of Anesthesia, Children's Hospital and Medical Center and University of Washington School of Medicine, Seattle
3 Division of Pediatric Laboratory Medicine, Dept of Pathology, Children's Hospital and Medical Center and University of Washington School of Medicine, Seattle

Group B streptococcus (GBS) is a common cause of severe infection in neonates. In the first days of life, GBS infection presents with sepsis, pneumonia, and cardiovascular collapse. Of those infected, between 25% and 75% will succumb to the disease.1 Nearly half of the children who survive neonatal GBS sepsis suffer significant long-term neurologic morbidity including seizures, mental retardation, hearing disorders, blindness, cerebral palsy, and developmental delays.1,2

The survivors of early-onset GBS pneumonitis appear to have a minimal risk of chronic pulmonary disease, but this has not been studied thoroughly. We describe a neonate with early-onset GBS sepsis and pneumonitis who developed severe respiratory failure requiring extracorporeal membrane oxygenation (ECMO) support.

Submitted on November 2, 1992
Accepted on January 28, 1993




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