PEDIATRICS Vol. 90 No. 5 November 1992, pp. 771-773
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Validating Current Immunization Practice With Young Infants

MICHAEL LEWIS PHD1, DOUGLAS S. RAMSAY PHD1, and STEPHEN J. SUOMI PHD2

1 Institute for the Study of Child Development, Robert Wood Johnson Medical School, New Brunswick, NJ
2 Laboratory of Comparative Ethology, National Institute of Child Health and Human Development

A recent change in standard pediatric practice on immunization of young infants has involved the administration of two injections during the same office visit as opposed to one injection per office visit. In the past, infants received a single injection at 2, 4, and 6 months of age, to immunize against diphtheria, tetanus, and pertussis. Now, young infants also receive a second injection, to immunize against Haemophilus influenzae type b. This change in procedure raises the question whether two injections during the same visit might be too stressful for young infants. A clear demonstration that two injections are no more stressful than one could provide sufficient evidence to allow pediatricians to feel confident that this new procedure is appropriate.

Submitted on October 30, 1991
Accepted on June 23, 1992




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