PEDIATRICS Vol. 90 No. 4 October 1992, pp. 646-647
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Steroids, Chronic Lung Disease, and Retinopathy of Prematurity

RICHARD A. EHRENKRANZ MD1

1 Division of Perinatal Medicine, Dept of Pediatrics, Yale University School of Medicine, New Haven, CT

This issue of Pediatrics contains two conflicting, retrospective observational studies concerning the relation between steroid therapy for chronic lung disease (CLD) and the need for cryotherapy for severe retinopathy of prematurity (ROP). Batton et al1 noted that more infants treated with dexamethasone for CLD needed cryotherapy for ROP, whereas Sobel and Philip2 found that steroid therapy for CLD did not affect the number of infants who needed cryotherapy for ROP. In fact, Sobel and Philip suggest that prolonged (>24 days) treatment with steroids may actually reduce the likelihood that ROP will reach "threshold" criteria for cryotherapy. Are these reports really contradictory?




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