PEDIATRICS Vol. 9 No. 6 June 1952, pp. 682-695
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HEREDITARY SEXUAL PRECOCITY

Report of a Family with 27 Affected Members

A. WILMOT JACOBSEN M.D.1 and MADGE T. MACKLIN M.D.1

1 The Department of Pediatrics, University of Buffalo School of Medicine, and the Children's Hospital of Buffalo, Buffalo, N.Y.

A family is reported in which 27 males were affected with precocious somatic and sexual development.

The trait is shown to be dependent upon a sex-limited autosomal gene with a little less than complete penetrance.

Submitted on December 20, 1951