PEDIATRICS Vol. 9 No. 5 May 1952, pp. 534-543
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TETANY AND PARATHYROID HYPERPLASIA IN THE NEWBORN INFANT: INFLUENCE OF DIETARY PHOSPHATE LOAD

LYTT I. GARDNER M.D.1

1 The Burnham Memorial Hospital for Children, Massachusetts General Hospital, Boston, and the Harriet Lane Home, the Johns Hopkins Hospital, Baltimore.

Three cases of newborn tetany are described, pointing out the relationship between dietary phosphate load and the manifestations of this disease.

An additional three newborn infants are described who showed other symptomatology than tetany in association with dietary phosphate load.

[See Table 1 in Source Pdf].

Data concerning diet, cause of death and degree of parathyroid hyperplasia are tabulated in eight newborns who were found to have parathyroid hyperplasia at autopsy. Similar data are tabulated on eight newborns and five older children who were found to have normal parathyroid glands at autopsy.

Several other factors possibly involved in newborn tetany and newborn parathyroid hyperplasia are discussed. The importance of measuring serum inorganic P in the differential diagnosis of neonatal distress is pointed out.

Submitted on October 31, 1951