PEDIATRICS Vol. 9 No. 1 January 1952, pp. 32-37
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BUTANOL-EXTRACTABLE IODINE IN THE SERUM OF INFANTS

EVELYN B. MAN PH.D.1, DONALD E. PICKERING M.D.1, JAMES WALKER M.D.1, and ROBERT E. COOKE M.D.1

1 The Departments of Internal Medicine and Pediatrics, Yale University School of Medicine, New Haven, Conn.

The difference between SPI and BEI in blood from the umbilical cord or from infants is no greater than the difference noted in the blood of adults. The average differences, SPI-BEI, in both are 0.4 to 0.5 gamma %.

SPI and BEI of cord blood do not differ significantly from those of the mother's blood taken during delivery and, therefore, cannot be used to measure the BEI of the infant during the first weeks of life. In contrast the concentrations of fatty acid and cholesterol of the serum from cord blood was only about one-third as great as that of maternal blood.

In the first days of life SPI and BEI rise sharply. In 12 of 13 infants 2 to 6 days old the BEIs were between 7.0 and 11.7 gamma %, values indicative of hyperthyroidism in adults.

Data on children from birth to 16 years of age suggest that the normal range may remain higher than that of adults for as long as seven years.

Submitted on July 19, 1951