PEDIATRICS Vol. 89 No. 6 June 1992, pp. 1129-1130
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Neurotoxicity of Lorazepam in a Premature Infant

CATHERINE M. G. CRONIN MD1

1 E3003 Section of Neonatology, St. Boniface General Hospital, 409 Tache Avenue, Winnipeg, Manitoba, Canada R2H 2A6

To the Editor.—

Recently, I have observed several cases of stereotypic movements following injection of lorazepam in premature infants and wish to alert my colleagues to a potential cause of neurotoxicity.

Case 1

CASE REPORTS

A male neonate was born in a peripheral hospital at 24 weeks gestation. Apgar scores were 2 at 1 minute and 6 at 5 minutes. He weighed 680 g and was transferred to a tertiary care institution at 20 hours of life.


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