PEDIATRICS Vol. 89 No. 4 April 1992, pp. 758-760
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Is It Practical to Screen for Familial Vesicoureteral Reflux Within a Private Pediatric Practice?

J. N. Peeden Jr MD1 and H. Norman Noe MD2

1 From The University of Teessee, Department of Pediatrics, adn Pediatric Associates, Knoxville, Tennessee
2 From the Department of Urology, Divisio of Pediatric Urology, Memphis, Tennessee

A prospective study was established within a private pediatric practice to identify the incidence and severity of vesicoureteral reflux in the siblings of patients known to have reflux. Twenty-four siblings of 18 children with reflux were studied. Eleven of these siblings were found to have reflux for an incidence of 46%. The risk of reflux in siblings of known children with reflux is thus significant and, at least in this study, compares with the risk of reflux after urinary tract infection. The outcome of the sibling group is discussed, along with our thoughts on the possible modes of inheritance of this disorder.

Key Words: vesicoureteral reflux • asymptomatic siblings of children with reflux • inheritance

Submitted on June 24, 1991
Accepted on November 26, 1991




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