PEDIATRICS Vol. 88 No. 5 November 1991, pp. 893-897
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Amitai, Y.
Right arrow Articles by Cosgrove, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Amitai, Y.
Right arrow Articles by Cosgrove, E.

Residential Deleading: Effects on the Blood Lead Levels of Lead-Poisoned Children

Yona Amitai MD1, Mary Jean Brown RN2, John W. Graef MD3, and Edward Cosgrove PhD2

1 The Division of Clinical Pharmacology and Toxicology, the Children's Hospital Medical Center, Boston
2 The Massachusetts Childhood Lead Poisoning Prevention Program, Boston
3 The Department of Pediatrics, Harvard Medical School, Boston

Acute elevations of venous blood lead levels (PbB) are periodically reported in children with chronic lead poisoning, during deleading of their houses. To evaluate this phenomenon 114 preschool children who entered the Massachusetts Childhood Lead Poisoning Prevention Program case management system during 1984 and 1985 were retrospectively studied. PbB increased from a mean (±SE) of 1.76 ± 0.03 µmol/L (36.4 ± 0.6 µg/dL) prior to deleading to 2.03 ± 0.07 µmol/L (42.1 ± 1.5 µg/dL) during deleading (P < .001). Among 41 subjects for whom deleading was done by dry scraping and sanding, the mean mid-deleading PbB was higher than the pre-deleading PbB by 0.44 ± 0.12 µmol/L (9.1 ± 2.4 µg/dL). However, when deleading was done by covering or replacement of painted surfaces in the residences of 12 subjects, mid-deleading PbB decreased 0.11 ± 0.12 µmol/L (2.25 ± 2.4 µg/dL)(P < .005). In a subset of 59 subjects who had no chelation therapy and were available for follow-up 250 ± 14 days after completion of deleading, PbB had decreased from 1.72 ± 0.04 µmol/L (35.7 ± 0.9 µg/dL) to 1.24 ± 0.04 µmol/L (25.5 ± 0.9 µg/dL) (P < .001). The long-term effect of deleading is a significant reduction in PbB. However, deleading resulted in a significant, albeit transient, increase in PbB.

Key Words: lead poisoning • prevention • control • children

Submitted on July 13, 1990
Accepted on December 5, 1990




This article has been cited by other articles:


Home page
 PediatricsHome page
M. J. Brown, P. McLaine, S. Dixon, and P. Simon
A Randomized, Community-Based Trial of Home Visiting to Reduce Blood Lead Levels in Children
Pediatrics, January 1, 2006; 117(1): 147 - 153.
[Abstract] [Full Text] [PDF]

Home page
 Health Promot PractHome page
D. Harrington, P. Scholz, G. Lomax, H. Stahlschmidt, J. Vannoy, and B. Materna
Can Half-Day Trainings Motivate Small Contractors to Address Lead Safety?
Health Promot Pract, July 1, 2004; 5(3): 297 - 305.
[Abstract] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
R. A. Gordon, G. Roberts, Z. Amin, R. H. Williams, and F. P. Paloucek
Aggressive Approach in the Treatment of Acute Lead Encephalopathy With an Extraordinarily High Concentration of Lead
Arch Pediatr Adolesc Med, November 1, 1998; 152(11): 1100 - 1104.
[Abstract] [Full Text] [PDF]

Home page
 Eval RevHome page
J. P. Duckart
An Evaluation of the Baltimore Community Lead Education and Reduction Corps (CLEARCorps) Program
Eval Rev, June 1, 1998; 22(3): 373 - 402.
[Abstract] [PDF]

Home page
 CLIN PEDIATRHome page
S. L. Swindell, E. Charney, M. J. Brown, and J. Delaney
Home Abatement and Blood Lead Changes in Children With Class III Lead Poisoning
Clinical Pediatrics, September 1, 1994; 33(9): 536 - 541.
[Abstract] [PDF]

Home page
 JWatch GeneralHome page
IS HOME DELEADING SAFE
Journal Watch (General), November 15, 1991; 1991(1115): 6 - 6.
[Full Text]