PEDIATRICS Vol. 87 No. 4 April 1991, pp. 582
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Extraordinary Urinary Frequency

DAVID A. BLOOM 1, AILEEN SEDMAN 1, and JERI ZOUBEK 1

1 University of Michigan, Ann Arbor, Michigan 48105

In Reply.—

Thank you for your letter and the comment on our paper. Dr Colodny raises some important points.

Our main point is that children with isolated extraordinary daytime frequency do not need extensive hematologic, radiologic, urodynamic, and psychiatric studies nor do they need routinely vigorous pharmacologic treatment. Even oxybutynin chloride is not innocuous. In addition to heat intolerance, facial flushing, and dry mouth, we have seen it cause attention deficits at school, hair loss, irritability, constipation, diarrhea, and dental problems, so we are reluctant to use this as liberally as we would a placebo.