1 Division of Medical Genetics, RG-25, University of Washington, Seattle, Washington 98105
To the Editor.
A recent paper in Pediatrics by Bard and Prosmanne1 described an elevation of fetal hemoglobin (Hb-F) production in infants with bronchopulmonary dysplasia (BPD) and oxygen dependency. The authors described a novel approach to the evaluation of occult hypoxemia in infants, with potential application in a wide range of disorders. However, in their paper the etiology of the elevation of Hb-F production in BPD patients may have been due to factors other than pulmonary disease.