PEDIATRICS Vol. 87 No. 2 February 1991, pp. 199-203
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Ehrlichiosis in Children

John R. Harkess MD1, S. A. Ewing DVM, PhD2, Timothy Brumit MD3, and Charles R. Mettry DO4

1 From the Epidemiology Service, Oklahoma State Department of Health, Oklahoma City
2 From the Department of Veterinary Parasitology, Microbiology, and Public Health, College of Veterinary Medicine, Oklahoma State University, Stillwater
3 Texoma Medical Center, Denison, Texas
4 Valley View Regional Hospital, Ada, Oklahoma

Tick-borne rickettsiae of the genus Ehrlichia have recently been recognized as a cause of human illness in the United States. In the years 1986-1988, 10 cases of ehrlichiosis were diagnosed in children in Oklahoma. Fever and headache were universal; myalgias, nausea, vomiting, and anorexia were also common. Rash was observed in six patients but was a prominent finding in only one. Leukopenia, lymphopenia, and thrombocytopenia were common laboratory abnormalities. Six patients were treated with tetracycline, three with chloramphenicol, and one was not treated with antibiotics; all recovered. The onset of illness in spring and early summer for most cases paralleled the time when Amblyomma americanum and Dermacentor variabilis are most active, suggesting that one or both ticks may be vectors of human ehrlichiosis in Oklahoma.

Key Words: Ehrlichia • ticks • ehrlichiosis

Submitted on September 11, 1989
Accepted on January 18, 1990




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