PEDIATRICS Vol. 83 No. 6 June 1989, pp. 1003-1006
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Suga, S.
Right arrow Articles by Hirata, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Suga, S.
Right arrow Articles by Hirata, S.

Human Herpesvirus-6 Infection (Exanthem Subitum) Without Rash

Sadao Suga MD1, Tetsushi Yoshikawa MD1, Yoshizo Asano MD1, Takehiko Yazaki MD1, and Shoji Hirata MD1

1 The Departments of Pediatrics, Fujita Gakuen Health University School of Medicine, Toyoake, Aichi, and Mino Municipal Hospital, Mino, Gifu, Japan

Two patients with a three-day febrile episode in whom exanthem subitum was expected showed no appearance of skin eruption after subsidence of the fever. Virus was isolated from peripheral blood mononuclear cells in the acute stage, which was identified by the cytopathic effects of infected cells and the specific immunofluorescent staining of the cells with convalescent sera from exanthem subitum, but the virus could not be isolated from those in the convalescent stage. The morphology of the virus was similar to herpes group virus. There were seroconversions against representative strain of the causative agent of exanthem subitum in the two patients. The results indicated the presence of atypical clinical course of exanthem subitum.

Key Words: exanthem subitum • human herpesvirus-6 • viremia • atypical roseola • virus isolation

Submitted on May 18, 1988
Accepted on August 8, 1988




This article has been cited by other articles:


Home page
 CVIHome page
S. LaCroix, J. A. Stewart, M. E. Thouless, and J. B. Black
An Immunoblot Assay for Detection of Immunoglobulin M Antibody to Human Herpesvirus 6
Clin. Vaccine Immunol., September 1, 2000; 7(5): 823 - 827.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. Suga, T. Yoshikawa, Y. Kajita, T. Ozaki, and Y. Asano
Prospective Study of Persistence and Excretion of Human Herpesvirus-6 in Patients With Exanthem Subitum and Their Parents
Pediatrics, October 1, 1998; 102(4): 900 - 904.
[Abstract] [Full Text] [PDF]