PEDIATRICS Vol. 83 No. 2 February 1989, pp. 293-308
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Human Immunodeficiency Virus Infection in Childhood, Adolescence, and Pregnancy: A Status Report and National Research Agenda

Stephen W. Nicholas MD1, Diane L. Sondheimer MS, MPH1, Anne D. Willoughby MD, MPH1, Sumner J. Yaffe MD1, and Samuel L. Katz MD1

1 The Columbia University Pediatric AIDS Program at Babies Hospital and Harlem Hospital, New York; Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research for Mothers and Children, National Institute of Child Health and Human Development, Bethesda, Maryland; and the Department of Pediatrics, Duke University Medical Center, Durham, North Carolina

During the first half of this decade, much new information about the acquired immunodeficiency syndrome (AIDS) became available, including landmark reports of the syndrome in children from Oleske et al, Rubinstein et al, and Scott et al; descriptions of AIDS in pregnancy by Wetli et al, Rawlinson et al, and Minkoff et al; and discovery of the agent that causes AIDS, the human immunodeficiency virus (HIV, formerly called HTLV-III/LAV).

The first sets of health guidelines pertaining to HIV-infected children and adolescents in school, day-care and foster care settings were published by the American Academy of Pediatrics' Committee on Infectious Diseases in March 1986 and 1987. In 1987, the Surgeon General's Workshop on Children With HIV Infection and Their Families provided the first comprehensive set of recommendations relevant to the provision of pediatric and obstetrical care to infected mothers, infants, children, and adolescents. Most recently, during February 1988, the Secretary of Health and Human Services formed the Secretary's Work Group on Pediatric HIV Infection and Disease that consisted of members from each of the health and human services agencies, including the Social Security Administration and the Health Care Financing Administration. The broad mandate of this group was to make recommendations to facilitate the removal of barriers to care, treatment, and financial burdens of children and adolescents with HIV infection and their families.

In contrast, HIV infection has not received sufficiently widespread attention from the obstetric, pediatric, or adolescent research communities. The uneven geographic distribution of the disease; its associated social, legal, and ethical complexities; and the lack of sufficient research monies all have contributed to this problem.

Submitted on October 14, 1988
Accepted on October 14, 1988




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