PEDIATRICS Vol. 83 No. 1 January 1989, pp. 100
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SIX REASONS FOR CONDUCTING A META-ANALYSIS

Student

1. To obtain a more stable estimate of the effect of treatment

2. To examine variability between trials and assess the generalizability of results

3. To perfrom subgroup analyses

4. To strengthen submissions on drug efficacy to licensing bodies such as the FDA

5. To identify the need for major trials

6. To put any one trial result into perspective by examining all similar trials