PEDIATRICS Vol. 82 No. 6 December 1988, pp. 951-952
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d-Penicillamine and Retinopathy of Prematurity

LAJOS LAKATOS MD1

1 Department of Pediatrics, Kenézy Gyula County Hospital, H-4043 Debrecen, Bartók Béla u 4, Hungary

To the Editor.—

The letter to the editor by Johnson et al1 and studies by others regarding vitamin E prophylaxis for retinopathy of prematurity suggest that further research into the prevention of retinopathy of prematurity should not be limited to vitamin E.

On the basis of clinical observations we reported that d-penicillamine treatment in the neonatal period was associated with a marked decrease in the incidence of severe retrolental fibroplasia among the very low birth weight infants.2