PEDIATRICS Vol. 82 No. 6 December 1988, pp. 874-879
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Postoperative Necrotizing Fasciitis in Children

Leo D. Farrell MD1, Stephen R. Karl MD1, Paul K. Davis MD1, Mark F. Bellinger MD1, and Thomas V. N. Ballantine MD1

1 From the Department of Surgery, University Hospital, the Milton S. Hershey Medical Center, the College of Medicine of the Pennsylvania State University, Hershey, Pennsylvania

Necrotizing fasciitis is a rapidly progressive soft tissue infection, involving the skin, subcutaneous tissue, and superficial fascia. It is a rare but life-threatening complication in the postoperative patient. In the last 7 years, we have treated four children in whom necrotizing fasciitis developed after appendectomy for ruptured appendix, bilateral inguinal herniorrhaphy, or gastrostomy closure. These four patients and seven well-described children from the literature with necrotizing fasciitis following surgery form the basis of this review. The ages ranged from six days to 15 years (ean 4.5 years). There were eight boys and three girls. There were five clean, five clean-contaminated, and one contaminated surgical procedures. No patient had evidence of malignancy or diabetes. Two of our four patients had evidence of failure to thrive. Only one patient had an intraabdominal abscess. In ten, the infection started in the abdominal wall; in one, the infection started in the chest wall. In our four patients, three had neutropenia and fever, four had tachycardia, and two had wound crepitation and radiographic evidence of subcutaneous gas. Cultures of all ten wounds were positive for bacteria; six were positive for more than one organism. Blood culture results were positive in five of five patients who died and in only two of five patients who survived. All survivors had wide surgical debridement and were treated with broad-spectrum antibiotics. The mortality rate was 45% in the whole series. In our four patients, the only death occurred in a child with Down syndrome and failure to thrive whose parents refused further therapy. Necrotizing fasciitis may complicate clean surgical procedures in children without risk factors. Septicemia is a late and ominous sign. Early wide surgical debridement and broad-spectrum antibiotic use are necessary for survival. Skin grafting is often required for late coverage of these defects.

Key Words: ecrotizing fasciitis • postoperative infection

Submitted on April 27, 1987
Accepted on August 26, 1987




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