PEDIATRICS Vol. 82 No. 6 December 1988, pp. 870-873
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Progress of a Harlequin Fetus to Nonbullous Ichthyosiform Erythroderma

Frances Lawlor MRCP11

1 From Coventry and Warwickshire Hospital, Coventry, England

The term harlequin fetus is used to describe the most severe form of congenital ichthyosis. All except one previously reported patient died during the first few weeks of life. The development of one such fetus to the age of 2 years 6 months is reported, along with a photographic record of progress. Details of the progress of another harlequin fetus to 6 months of age are given. The clinical diagnosis of the former patient is nonbullous ichthyosiform erythroderma.

Key Words: harlequin fetus • autosomal recessive disorder • nonbullous ichthyosiform erythroderma • ichthyosis

Submitted on March 20, 1987
Accepted on August 26, 1988




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