1 From the Department of Social Medicine, Faculty of Medicine, Federal University of Pelotas, Pelotas, RS, Brazil, and the Tropical Epidemiology Unit and the Evaluation and Planning Centre, London School of Hygiene and Tropical Medicine, London
The association between birth weight and infant mortality from infectious diseases was investigated in a population-based case-control study in two urban areas in southern Brazil. All deaths of children, seven to 364 days of age, occurring in a year were studied and the parents of the 357 infants dying of an infectious cause were interviewed, as were the parents of two neighborhood control infants for each case. Low birth weight infants (<2,500 g) were found, after allowing for confounding factors, to be 2.3 (90% confidence interval = 1.6 to 3.4) times more likely to die of an infection than those of higher birth weight. The odds ratios were 2.0 (1.1 to 3.6) for deaths due to diarrhea, 1.9 (1.0 to 3.6) for respiratory infections, and 5.0 (1.3 to 18.6) for other infections. These estimates of the risks associated with low birth weight are considerably lower than those from studies in developed countries.
Key Words: birth weight infant mortality infectious disease diarrhea respiratory infection
Submitted on May 26, 1987
Accepted on July 31, 1987
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