PEDIATRICS Vol. 81 No. 5 May 1988, pp. 721-722
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Plea for Enhancing Neuronal Survival by Neurophysiologic Monitoring

MARTHA BUSHORE MD1

1 East Tennessee Children's Hospital, Knoxville

Drs Nussbaum and Maggi provide us with thought-provoking information in their prospective study of nearly drowned children who incurred severe anoxic ischemic encephalopathy and were in a flaccid state of coma on admission to the pediatric intensive care unit. In their discussion, they note that there is not a uniform approach to management of severely comatose, nearly drowned children. Although the rationale for the protective role of barbiturates in the presence of anoxic-ischemic encephalopathy has a strong scientific basis, results of their study indicate that clinical outcome of patients treated with barbiturates does not support the scientific basis for their use.